简历介绍

苗露，女，博士，副研究员，硕士生导师。2009年毕业于吉林大学，获理学学士学位；2014年毕业于吉林大学化学学院，获得博士学位。毕业后到中国科学院大连化学物理研究所工作至今，2018年晋升为副研究员。研究方向致力于蛋白的荧光标记与性能调控研究，利用基因工程技术，联合小分子荧光染料和荧光成像，通过对蛋白的合理设计与改造，实现对蛋白功能研究和性能的调控。在Chem, Sci., Cell Chem. Biol., JACS, ACS nano, Adv. Sci.等学术期刊上发表论文60余篇，授权专利5件，承担国家自然科学基金，辽宁省市，研究所基金多项。

代表论著

1.     Xuelian Zhou, Lu Miao*, Wei Zhou, Yonghui Chen, Yiyan Ruan, Xiang Wang, Guangying Wang, Pengjun Bao, Qinglong Qiao* and Zhaochao Xu*, Enhancing Photostability of Red Fluorescent Proteins through FRET with Si-Rhodamine for Dynamic Super-Resolution Fluorescence Imaging, Chem. Sci., 2025, 16, 10476-10486.

 

2.     Xuelian Zhou, Lu Miao*, Ning Xu, Yonghui Chen, Jinjing Shi, Jinhua Zhou, Guangying Wang, Qinglong Qiao*, Zhaochao Xu*, Chemigenetic Encoding of Fluorescent Dyes Enables High-Fidelity and Wash-Free Imaging of Proteins in Live Cells, Adv. Sci., 2025, e05967, 1-12.  

 

3.     Chunyu Yan, Qinglong Qiao, Wei Zhou, Xuelian Zhou, Yonghui Chen, Lu Miao*, Zhaochao Xu*. FRET-based in vitro Assay for Rapid Detecting of SARS-CoV-2 Entry Inhibitors, Chin. Chem. Lett., 2025, 36, 110258.

 

4.     Yan Zhang, Ning Xu, Chunyu Yan, Xuelian Zhou, Qinglong Qiao, Lu Miao*, and Zhaochao Xu*, Live-Cell Imaging to Resolve Salt-Induced Liquid–Liquid Phase Separation of FUS Protein by Dye Self-Labeling, Chem. Biomed. Imaging, 2024, 2, 70- 80

 

5.     Lu Miao, Chunyu Yan, Yingzhu Chen, Wei Zhou, Xuelian Zhou, Qinglong Qiao, Zhaochao Xu*, SIM imaging resolves endocytosis of SARS-CoV-2 spike RBD in living cells, Cell Chemical Biology, 2023, 30, 248-260.  

 

6.     Lu Miao, Wei Zhou, Chunyu Yan, Yuebin Zhang, Qinglong Qiao, Xuelian Zhou, Yingzhu Chen, Guangying Wang, Zhendong Guo, Jun Liu, Hailong Piao, Xia Pan, Mengxue Yan, Weijie Zhao, Guohui Li*, Yueqing Li*, Zhaochao Xu*, Rapid screening of SARS-CoV-2 inhibitors via ratiometric fluorescence of RBDeACE2 complexes in living cells by competitive binding, Acta Pharmaceutica Sinica B, 2022, 12, 3739-3742.